Antigenic Relatedness of Norovirus GII.4 Variants Determined by Human Challenge Sera

The GII.4 noroviruses (NoVs) are a single genotype that is responsible for over 50% of NoV gastroenteritis epidemics worldwide. However, GII.4 NoVs have been found to undergo antigenic drifts, likely selected by host herd immunity, which raises an issue for vaccine strategies against NoVs. We previo...

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Bibliographic Details
Main Authors: Dai, Ying-Chun, Zhang, Xu-Fu, Xia, Ming, Tan, Ming, Quigley, Christina, Lei, Wen, Fang, Hao, Zhong, Weiming, Lee, Bonita, Pang, Xiaoli, Nie, Jun, Jiang, Xi
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411064/