Interactions of antiparasitic sterols with sterol 14α-demethylase (CYP51) of human pathogens
Sterol 14α-demethylase is a validated and an attractive drug target in human protozoan parasites. Pharmacological inactivation of this important enzyme has proven very effective against fungal infections, and it is a target that is being exploited for new antitrypanosomal and antileishmanial chemoth...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer International Publishing
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410773/ |