Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats

Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats

Aims: Early phagocytosis of glucose-6-phosphate dehydrogenase (G6PD)-deficient erythrocytes parasitized by Plasmodium falciparum were shown to protect G6PD-deficient populations from severe malaria. Here, we investigated the mechanism of a novel antimalarial series, namely 3-[substituted-benzyl]-men...

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Bibliographic Details
Main Authors: Bielitza, Max, Belorgey, Didier, Ehrhardt, Katharina, Johann, Laure, Lanfranchi, Don Antoine, Gallo, Valentina, Schwarzer, Evelin, Mohring, Franziska, Jortzik, Esther, Williams, David L., Becker, Katja, Arese, Paolo, Elhabiri, Mourad, Davioud-Charvet, Elisabeth
Format: Online
Language:English
Published: Mary Ann Liebert, Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410756/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410756/

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