Combinatorial code governing cellular responses to complex stimuli

Cells adapt to their environment through the integration of complex signals. Multiple signals can induce synergistic or antagonistic interactions, currently considered as homogenous behaviours. Here, we use a systematic theoretical approach to enumerate the possible interaction profiles for outputs...

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Bibliographic Details
Main Authors: Cappuccio, Antonio, Zollinger, Raphaël, Schenk, Mirjam, Walczak, Aleksandra, Servant, Nicolas, Barillot, Emmanuel, Hupé, Philippe, Modlin, Robert L., Soumelis, Vassili
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410637/