The transcription factor KLF2 restrains CD4+ T follicular helper cell differentiation

The transcription factor KLF2 restrains CD4+ T follicular helper cell differentiation

T follicular helper (Tfh) cells are essential for efficient B cell responses, yet the factors that regulate differentiation of this CD4+ T cell subset are incompletely understood. Here we found that the KLF2 transcription factor serves to restrain Tfh cell generation. Induced KLF2 deficiency in acti...

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Bibliographic Details
Main Authors: Lee, June-Yong, Skon, Cara N., Lee, You Jeong, Oh, Soohwan, Taylor, Justin J., Malhotra, Deepali, Jenkins, Marc K., Rosenfeld, M. Geoffrey, Hogquist, Kristin A., Jameson, Stephen C.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409658/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409658/

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