Cell death and morphogenesis during early mouse development: Are they interconnected?

Shortly after implantation the embryonic lineage transforms from a coherent ball of cells into polarized cup shaped epithelium. Recently we elucidated a previously unknown apoptosis-independent morphogenic event that reorganizes the pluripotent lineage. Polarization cues from the surrounding basemen...

Full description

Bibliographic Details
Main Authors: Bedzhov, Ivan, Zernicka-Goetz, Magdalena
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409078/