PDGF beta targeting in cervical cancer cells suggest a fine-tuning of compensatory signalling pathways to sustain tumourigenic stimulation

The platelet-derived growth factor (PDGF) signalling pathway has been reported to play an important role in human cancers by modulating autocrine and paracrine processes such as tumour growth, metastasis and angiogenesis. Several clinical trials document the benefits of targeting this pathway; howev...

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Bibliographic Details
Main Authors: Tudoran, Oana Mihaela, Soritau, Olga, Balacescu, Loredana, Pop, Laura, Meurice, Guillaume, Visan, Simona, Lindberg, Staffan, Eniu, Alexandru, Langel, Ulo, Balacescu, Ovidiu, Berindan-Neagoe, Ioana
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407607/