Stn1 is critical for telomere maintenance and long-term viability of somatic human cells

Stn1 is critical for telomere maintenance and long-term viability of somatic human cells

Disruption of telomere maintenance pathways leads to accelerated entry into cellular senescence, a stable proliferative arrest that promotes aging-associated disorders in some mammals. The budding yeast CST complex, comprising Cdc13, Stn1, and Ctc1, is critical for telomere replication, length regul...

Full description

Bibliographic Details
Main Authors: Boccardi, Virginia, Razdan, Neetu, Kaplunov, Jessica, Mundra, Jyoti J, Kimura, Masayuki, Aviv, Abraham, Herbig, Utz
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406666/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406666/

Similar Items