Extracellular Regulated Kinase Phosphorylates Mitofusin 1 to Control Mitochondrial Morphology and Apoptosis

Controlled changes in mitochondrial morphology participate in cellular signaling cascades. However, the molecular mechanisms modifying mitochondrial shape are largely unknown. Here we show that the mitogen-activated protein (MAP) kinase cascade member extracellular-signal-regulated kinase (ERK) phos...

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Bibliographic Details
Main Authors: Pyakurel, Aswin, Savoia, Claudia, Hess, Daniel, Scorrano, Luca
Format: Online
Language:English
Published: Cell Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405354/