Cu2+-RGDFRGDS: exploring the mechanism and high efficacy of the nanoparticle in antithrombotic therapy

Thrombosis disease has been the leading cause of morbidity and mortality worldwide. In the discovery of antithrombotic agents, three complexes of Cu2+ and repetitive arginine-glycine-aspartic acid (RGD) sequences, Cu(II)-Arg-Gly-Asp-Ser-Arg-Gly-Asp-Ser (Cu[II]-4a), Cu(II)-Arg-Gly-Asp-Val-Arg-Gly-Asp...

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Bibliographic Details
Main Authors: Wu, Jianhui, Wang, Yuji, Wang, Yaonan, Zhao, Ming, Zhang, Xiaoyi, Gui, Lin, Zhao, Shurui, Zhu, Haimei, Zhao, Jinghua, Peng, Shiqi
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404989/