Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immune responses against cancer stem cells

The inability to target cancer stem cells (CSC) may be a significant factor contributing to treatment failure. We have developed a strategy to target the CSC populations in melanoma and squamous cell carcinoma using CSC lysate-pulsed dendritic cells (DCs). The CSC-DC vaccine was administered in the...

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Bibliographic Details
Main Authors: Lu, Lin, Tao, Huimin, Chang, Alfred E, Hu, Yangyang, Shu, Guoshun, Chen, Quanning, Egenti, Martin, Owen, John, Moyer, Jeffrey S, Prince, Mark EP, Huang, Shiang, Wicha, Max S, Xia, Jian-Chuan, Li, Qiao
Format: Online
Language:English
Published: Taylor & Francis 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404925/