A method to associate all possible combinations of genetic and environmental factors using GxE landscape plot

Genome-wide association studies (GWAS) and linkage analysis has identified many single nucleotide polymorphisms (SNPs) related to disease. There are many unknown SNPs whose minor allele frequencies (MAFs) as low as 0.005 having intermediate effects with odds ratio between 1.5~3.0. Low frequency vari...

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Bibliographic Details
Main Authors: Nagaie, Satoshi, Ogishima, Soichi, Nakaya, Jun, Tanaka, Hiroshi
Format: Online
Language:English
Published: Biomedical Informatics 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404419/