CYLD Regulates Noscapine Activity in Acute Lymphoblastic Leukemia via a Microtubule-Dependent Mechanism

Noscapine is an orally administrable drug used worldwide for cough suppression and has recently been demonstrated to disrupt microtubule dynamics and possess anticancer activity. However, the molecular mechanisms regulating noscapine activity remain poorly defined. Here we demonstrate that cylindrom...

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Bibliographic Details
Main Authors: Yang, Yunfan, Ran, Jie, Sun, Lei, Sun, Xiaodong, Luo, Youguang, Yan, Bing, Tala, Liu, Min, Li, Dengwen, Zhang, Lei, Bao, Gang, Zhou, Jun
Format: Online
Language:English
Published: Ivyspring International Publisher 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402491/