GABAB receptor phosphorylation regulates KCTD12-induced K+ current desensitization

GABAB receptors assemble from GABAB1 and GABAB2 subunits. GABAB2 additionally associates with auxiliary KCTD subunits (named after their K+ channel tetramerization-domain). GABAB receptors couple to heterotrimeric G–proteins and activate inwardly-rectifying K+ channels through the βγ subunits releas...

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Bibliographic Details
Main Authors: Adelfinger, Lisa, Turecek, Rostislav, Ivankova, Klara, Jensen, Anders A., Moss, Stephen J., Gassmann, Martin, Bettler, Bernhard
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402209/