Reptin Regulates DNA Double Strand Breaks Repair in Human Hepatocellular Carcinoma

Reptin/RUVBL2 is overexpressed in most hepatocellular carcinomas and is required for the growth and viability of HCC cells. Reptin is involved in several chromatin remodeling complexes, some of which are involved in the detection and repair of DNA damage, but data on Reptin involvement in the repair...

Full description

Bibliographic Details
Main Authors: Raymond, Anne-Aurélie, Benhamouche, Samira, Neaud, Véronique, Di Martino, Julie, Javary, Joaquim, Rosenbaum, Jean
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398330/