Snake neurotoxin α-bungarotoxin is an antagonist at native GABAA receptors

The snake neurotoxin α-bungarotoxin (α-Bgtx) is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs) and is widely used to study their function and cell-surface expression. Increasingly, α-Bgtx is also used as an imaging tool for fluorophore-labelling studies, and given the structu...

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Bibliographic Details
Main Authors: Hannan, Saad, Mortensen, Martin, Smart, Trevor G.
Format: Online
Language:English
Published: Pergamon Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398322/