Synaptotagmin VII Restricts Fusion Pore Expansion during Lysosomal Exocytosis

Synaptotagmin is considered a calcium-dependent trigger for regulated exocytosis. We examined the role of synaptotagmin VII (Syt VII) in the calcium-dependent exocytosis of individual lysosomes in wild-type (WT) and Syt VII knockout (KO) mouse embryonic fibroblasts (MEFs) using total internal reflec...

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Bibliographic Details
Main Authors: Jaiswal, Jyoti K, Chakrabarti, Sabyasachi, Andrews, Norma W, Simon, Sanford M
Format: Online
Language:English
Published: Public Library of Science 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC439782/