Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice

Merkel cell carcinoma (MCC) is a rare and deadly neuroendocrine skin tumor frequently associated with clonal integration of a polyomavirus, MCPyV, and MCC tumor cells express putative polyomavirus oncoproteins small T antigen (sTAg) and truncated large T antigen (tLTAg). Here, we show robust transfo...

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Bibliographic Details
Main Authors: Verhaegen, Monique E., Mangelberger, Doris, Harms, Paul W., Vozheiko, Tracy D., Weick, Jack W., Wilbert, Dawn M., Saunders, Thomas L., Ermilov, Alexandre N., Bichakjian, Christopher K., Johnson, Timothy M., Imperiale, Michael J., Dlugosz, Andrzej A.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397111/