Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction
Chronic obstructive lung disease determines morbidity and mortality of patients with cystic fibrosis (CF). CF airways are characterized by a nonresolving neutrophilic inflammation. After pathogen contact or prolonged activation, neutrophils release DNA fibres decorated with antimicrobial proteins, f...
Main Authors: | , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397025/ |