Identification of TMPRSS6 cleavage sites of hemojuvelin

Identification of TMPRSS6 cleavage sites of hemojuvelin

Hemojuvelin (HJV), the coreceptor of the BMP-SMAD pathway that up-regulates hepcidin transcription, is a repulsive guidance molecule (RGMc) which undergoes a complex intracellular processing. Following autoproteolysis, it is exported to the cell surface both as a full-length and a heterodimeric prot...

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Bibliographic Details
Main Authors: Rausa, Marco, Ghitti, Michela, Pagani, Alessia, Nai, Antonella, Campanella, Alessandro, Musco, Giovanna, Camaschella, Clara, Silvestri, Laura
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395201/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395201/

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