MiR-1188 at the imprinted Dlk1-Dio3 domain acts as a tumor suppressor in hepatoma cells

MiR-1188 at the imprinted Dlk1-Dio3 domain is a novel player in hepatocellular carcinoma. MiR-1188 expression was found to be decreased in hepatoma cells, and, when overexpressed, miR-1188 inhibited Bcl2 and Sp1 expression, suppressed cell proliferation and migration, promoted apoptosis in vitro, an...

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Bibliographic Details
Main Authors: Cui, Wei, Huang, Zhijun, He, Hongjuan, Gu, Ning, Qin, Geng, Lv, Jie, Zheng, Tao, Sugimoto, Kenkichi, Wu, Qiong
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395123/