Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure

Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure

Treatment of decompensated heart failure often includes administration of levosimendan. Myeloperoxidase (MPO) is released during polymorphonuclear neutrophil (PMN) degranulation, and mediates dysregulation of vascular tone in heart failure. We evaluated the effects of levosimendan-treatment on MPO i...

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Bibliographic Details
Main Authors: Adam, Matti, Meyer, Sven, Knors, Henning, Klinke, Anna, Radunski, Ulf K., Rudolph, Tanja K., Rudolph, Volker, Spin, Joshua M., Tsao, Philip S., Costard-Jäckle, Angelika, Baldus, Stephan
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394753/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394753/

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