High Expression of c-kit mRNA Predicts Unfavorable Outcome in Adult Patients with t(8;21) Acute Myeloid Leukemia

High Expression of c-kit mRNA Predicts Unfavorable Outcome in Adult Patients with t(8;21) Acute Myeloid Leukemia

The reason that a certain subgroup of acute myeloid leukemia (AML) patients with t(8;21) translocation (generating the AML1/ETO fusion gene) displays a poor survival remains elusive. The proto-oncogene c-kit is expressed in approximately 80% of AML cases. The kinase domain mutation of the c-kit gene...

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Bibliographic Details
Main Authors: Gao, Xiaoning, Lin, Ji, Gao, Li, Deng, Ailing, Lu, Xiaolin, Li, Yonghui, Wang, Lili, Yu, Li
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393018/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393018/

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