Lipidic cubic phase serial millisecond crystallography using synchrotron radiation

This article describes the structure determination of a membrane protein by serial injection of microcrystals in lipidic cubic phases into a synchrotron microfocus beam. The method is discussed with respect to serial femtosecond crystallography at free-electron lasers.

Bibliographic Details
Main Authors: Nogly, Przemyslaw, James, Daniel, Wang, Dingjie, White, Thomas A., Zatsepin, Nadia, Shilova, Anastasya, Nelson, Garrett, Liu, Haiguang, Johansson, Linda, Heymann, Michael, Jaeger, Kathrin, Metz, Markus, Wickstrand, Cecilia, Wu, Wenting, Båth, Petra, Berntsen, Peter, Oberthuer, Dominik, Panneels, Valerie, Cherezov, Vadim, Chapman, Henry, Schertler, Gebhard, Neutze, Richard, Spence, John, Moraes, Isabel, Burghammer, Manfred, Standfuss, Joerg, Weierstall, Uwe
Format: Online
Language:English
Published: International Union of Crystallography 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392771/