Contribution of Large Region Joint Associations to Complex Traits Genetics

A polygenic model of inheritance, whereby hundreds or thousands of weakly associated variants contribute to a trait’s heritability, has been proposed to underlie the genetic architecture of complex traits. However, relatively few genetic variants have been positively identified so far and they colle...

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Bibliographic Details
Main Authors: Paré, Guillaume, Asma, Senay, Deng, Wei Q.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391841/