Synaptic dysfunction and septin protein family members in neurodegenerative diseases

Cognitive decline and disease progression in different neurodegenerative diseases typically involves synaptic dysfunction preceding the neuronal loss. The synaptic dysfunction is suggested to be caused by imbalanced synaptic plasticity i.e. enhanced induction of long-term depression and concomitantl...

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Bibliographic Details
Main Authors: Marttinen, Mikael, Kurkinen, Kaisa MA, Soininen, Hilkka, Haapasalo, Annakaisa, Hiltunen, Mikko
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391194/