Cooperativity leads to temporally-correlated fluctuations in the bacteriophage lambda genetic switch

Cooperative interactions are widespread in biochemical networks, providing the nonlinear response that underlies behavior such as ultrasensitivity and robust switching. We introduce a temporal correlation function—the conditional activity—to study the behavior of these phenomena. Applying it to the...

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Bibliographic Details
Main Authors: Shenker, Jacob Q., Lin, Milo M.
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389348/