RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction

Molecular pathways underlying the neurotoxicity and production of amyloid β protein (Aβ) represent potentially promising therapeutic targets for Alzheimer's disease (AD). We recently found that overexpression of the scaffolding protein RanBP9 increases Aβ production in cell lines and in transge...

Full description

Bibliographic Details
Main Authors: Woo, J A, Boggess, T, Uhlar, C, Wang, X, Khan, H, Cappos, G, Joly-Amado, A, De Narvaez, E, Majid, S, Minamide, L S, Bamburg, J R, Morgan, D, Weeber, E, Kang, D E
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385917/