Ubiquitin-specific proteases as therapeutic targets for the treatment of breast cancer

Key mediators of signaling pathways in breast cancer involve post-translational protein modification, primarily mediated through phosphorylation and ubiquitination. While previous studies focused on phosphorylation events, more recent analysis suggests that ubiquitin plays a parallel and equally imp...

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Bibliographic Details
Main Authors: Pal, Anupama, Donato, Nicholas J
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384352/