Human BDCA2+CD123+CD56+ dendritic cells (DCs) related to blastic plasmacytoid dendritic cell neoplasm represent a unique myeloid DC subset
Dendritic cells (DCs) comprise two functionally distinct subsets: plasmacytoid DCs (pDCs) and myeloid DCs (mDCs). pDCs are specialized in rapid and massive secretion of type I interferon (IFN-I) in response to nucleic acids through Toll like receptor (TLR)-7 or TLR-9. In this report, we characterize...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Higher Education Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383756/ |