Spontaneous Cdc42 Polarization Independent of GDI-Mediated Extraction and Actin-Based Trafficking

Spontaneous Cdc42 Polarization Independent of GDI-Mediated Extraction and Actin-Based Trafficking

The small Rho-family GTPase Cdc42 is critical for cell polarization and polarizes spontaneously in absence of upstream spatial cues. Spontaneous polarization is thought to require dynamic Cdc42 recycling through Guanine nucleotide Dissociation Inhibitor (GDI)-mediated membrane extraction and vesicle...

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Bibliographic Details
Main Authors: Bendezú, Felipe O., Vincenzetti, Vincent, Vavylonis, Dimitrios, Wyss, Romain, Vogel, Horst, Martin, Sophie G.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383620/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383620/

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