An LRP16-containing preassembly complex contributes to NF-κB activation induced by DNA double-strand breaks
The activation of NF-κB has emerged as an important mechanism for the modulation of the response to DNA double-strand breaks (DSBs). The concomitant SUMOylation and phosphorylation of IKKγ by PIASy and ATM, respectively, is a key event in this mechanism. However, the mechanism through which mammalia...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381070/ |