TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies

Frontotemporal lobar degeneration (FTLD) is one of the leading causes of dementia after Alzheimer’s disease. A high-ranking candidate to become a diagnostic marker for a major pathological subtype of FTLD is the transactive response DNA binding protein of 43 kDa (TDP-43). The main objective is to el...

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Bibliographic Details
Main Authors: Goossens, Joery, Vanmechelen, Eugeen, Trojanowski, John Q, Lee, Virginia MY, Van Broeckhoven, Christine, van der Zee, Julie, Engelborghs, Sebastiaan
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380254/