Enhanced Hepatogenic Transdifferentiation of Human Adipose Tissue Mesenchymal Stem Cells by Gene Engineering with Oct4 and Sox2

Adipose tissue mesenchymal stem cells (ATMSCs) represent an attractive tool for the establishment of a successful stem cell-based therapy in the field of liver regeneration medicine. ATMSCs overexpressing Oct4 and Sox2 (Oct4/Sox2-ATMSCs) showed enhanced proliferation and multipotency. Hence, we hypo...

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Bibliographic Details
Main Authors: Han, Sei-Myoung, Coh, Ye-Rin, Ahn, Jin-Ok, Jang, Goo, Yum, Soo Young, Kang, Sung-Keun, Lee, Hee-Woo, Youn, Hwa-Young
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376765/