Myeloid heme oxygenase-1 promotes metastatic tumor colonization in mice

Heme oxygenase-1 (HO-1) is a heme degradation enzyme with antioxidant and immune-modulatory functions. HO-1 promotes tumorigenesis by enhancing tumor cell proliferation and invasion. Whether HO-1 has an effect on cancer progression through stromal compartments is less clear. Here we show that the gr...

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Bibliographic Details
Main Authors: Lin, Heng-Huei, Chiang, Ming-Tsai, Chang, Po-Chiao, Chau, Lee-Young
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376439/