Myeloid heme oxygenase-1 promotes metastatic tumor colonization in mice
Heme oxygenase-1 (HO-1) is a heme degradation enzyme with antioxidant and immune-modulatory functions. HO-1 promotes tumorigenesis by enhancing tumor cell proliferation and invasion. Whether HO-1 has an effect on cancer progression through stromal compartments is less clear. Here we show that the gr...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
BlackWell Publishing Ltd
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376439/ |