Chronopharmacokinetics of once daily dosed aminoglycosides in hospitalized infectious patients
Background hospitalized patients with serious infections treated with aminoglycosides are at risk of developing nephrotoxicity. Previous clinical studies have shown that the pharmacokinetics of aminoglycosides in humans follow a circadian rhythm. Therefore, the time of administration could have impo...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer Netherlands
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375292/ |