A Voltage-Gated Calcium Channel Regulates Lysosomal Fusion with Endosomes and Autophagosomes and Is Required for Neuronal Homeostasis

A Voltage-Gated Calcium Channel Regulates Lysosomal Fusion with Endosomes and Autophagosomes and Is Required for Neuronal Homeostasis

Autophagy helps deliver sequestered intracellular cargo to lysosomes for proteolytic degradation and thereby maintains cellular homeostasis by preventing accumulation of toxic substances in cells. In a forward mosaic screen in Drosophila designed to identify genes required for neuronal function and...

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Bibliographic Details
Main Authors: Tian, Xuejun, Gala, Upasana, Zhang, Yongping, Shang, Weina, Nagarkar Jaiswal, Sonal, di Ronza, Alberto, Jaiswal, Manish, Yamamoto, Shinya, Sandoval, Hector, Duraine, Lita, Sardiello, Marco, Sillitoe, Roy V., Venkatachalam, Kartik, Fan, Hengyu, Bellen, Hugo J., Tong, Chao
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374850/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374850/

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