Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation
Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently...
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2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374307/ |
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pubmed-43743072015-03-27 Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation Misra, Satya Ranjan Shankar, Y. Uday Rastogi, Varun Maragathavalli, G. Case Report Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis. Medknow Publications & Media Pvt Ltd 2015-03 /pmc/articles/PMC4374307/ /pubmed/25821363 http://dx.doi.org/10.4103/0976-237X.152966 Text en Copyright: © Contemporary Clinical Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Misra, Satya Ranjan Shankar, Y. Uday Rastogi, Varun Maragathavalli, G. |
spellingShingle |
Misra, Satya Ranjan Shankar, Y. Uday Rastogi, Varun Maragathavalli, G. Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation |
author_facet |
Misra, Satya Ranjan Shankar, Y. Uday Rastogi, Varun Maragathavalli, G. |
author_sort |
Misra, Satya Ranjan |
title |
Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation |
title_short |
Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation |
title_full |
Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation |
title_fullStr |
Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation |
title_full_unstemmed |
Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation |
title_sort |
metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation |
description |
Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis. |
publisher |
Medknow Publications & Media Pvt Ltd |
publishDate |
2015 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374307/ |
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1613203749303484416 |