Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation

Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently...

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Main Authors: Misra, Satya Ranjan, Shankar, Y. Uday, Rastogi, Varun, Maragathavalli, G.
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374307/
id pubmed-4374307
recordtype oai_dc
spelling pubmed-43743072015-03-27 Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation Misra, Satya Ranjan Shankar, Y. Uday Rastogi, Varun Maragathavalli, G. Case Report Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis. Medknow Publications & Media Pvt Ltd 2015-03 /pmc/articles/PMC4374307/ /pubmed/25821363 http://dx.doi.org/10.4103/0976-237X.152966 Text en Copyright: © Contemporary Clinical Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Misra, Satya Ranjan
Shankar, Y. Uday
Rastogi, Varun
Maragathavalli, G.
spellingShingle Misra, Satya Ranjan
Shankar, Y. Uday
Rastogi, Varun
Maragathavalli, G.
Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation
author_facet Misra, Satya Ranjan
Shankar, Y. Uday
Rastogi, Varun
Maragathavalli, G.
author_sort Misra, Satya Ranjan
title Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation
title_short Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation
title_full Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation
title_fullStr Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation
title_full_unstemmed Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation
title_sort metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation
description Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374307/
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