Plastid establishment did not require a chlamydial partner
Primary plastids descend from the cyanobacterial endosymbiont of an ancient eukaryotic host, but the initial selective drivers that stabilized the association between these two cells are still unclear. One hypothesis that has achieved recent prominence suggests that the first role of the cyanobiont...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Nature Pub. Group
2015
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374161/ |
| id |
pubmed-4374161 |
|---|---|
| recordtype |
oai_dc |
| spelling |
pubmed-43741612015-04-07 Plastid establishment did not require a chlamydial partner Domman, Daryl Horn, Matthias Embley, T. Martin Williams, Tom A. Article Primary plastids descend from the cyanobacterial endosymbiont of an ancient eukaryotic host, but the initial selective drivers that stabilized the association between these two cells are still unclear. One hypothesis that has achieved recent prominence suggests that the first role of the cyanobiont was in energy provision for a host cell whose reserves were being depleted by an intracellular chlamydial pathogen. A pivotal claim is that it was chlamydial proteins themselves that converted otherwise unusable cyanobacterial metabolites into host energy stores. We test this hypothesis by investigating the origins of the key enzymes using sophisticated phylogenetics. Here we show a mosaic origin for the relevant pathway combining genes with host, cyanobacterial or bacterial ancestry, but we detect no strong case for Chlamydiae to host transfer under the best-fitting models. Our conclusion is that there is no compelling evidence from gene trees that Chlamydiae played any role in establishing the primary plastid endosymbiosis. Nature Pub. Group 2015-03-11 /pmc/articles/PMC4374161/ /pubmed/25758953 http://dx.doi.org/10.1038/ncomms7421 Text en Copyright © 2015, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Domman, Daryl Horn, Matthias Embley, T. Martin Williams, Tom A. |
| spellingShingle |
Domman, Daryl Horn, Matthias Embley, T. Martin Williams, Tom A. Plastid establishment did not require a chlamydial partner |
| author_facet |
Domman, Daryl Horn, Matthias Embley, T. Martin Williams, Tom A. |
| author_sort |
Domman, Daryl |
| title |
Plastid establishment did not require a chlamydial partner |
| title_short |
Plastid establishment did not require a chlamydial partner |
| title_full |
Plastid establishment did not require a chlamydial partner |
| title_fullStr |
Plastid establishment did not require a chlamydial partner |
| title_full_unstemmed |
Plastid establishment did not require a chlamydial partner |
| title_sort |
plastid establishment did not require a chlamydial partner |
| description |
Primary plastids descend from the cyanobacterial endosymbiont of an ancient eukaryotic host, but the initial selective drivers that stabilized the association between these two cells are still unclear. One hypothesis that has achieved recent prominence suggests that the first role of the cyanobiont was in energy provision for a host cell whose reserves were being depleted by an intracellular chlamydial pathogen. A pivotal claim is that it was chlamydial proteins themselves that converted otherwise unusable cyanobacterial metabolites into host energy stores. We test this hypothesis by investigating the origins of the key enzymes using sophisticated phylogenetics. Here we show a mosaic origin for the relevant pathway combining genes with host, cyanobacterial or bacterial ancestry, but we detect no strong case for Chlamydiae to host transfer under the best-fitting models. Our conclusion is that there is no compelling evidence from gene trees that Chlamydiae played any role in establishing the primary plastid endosymbiosis. |
| publisher |
Nature Pub. Group |
| publishDate |
2015 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374161/ |
| _version_ |
1613203667857440768 |