Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment

Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment

The generation of naïve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood. We have identified a mouse mutant, bloto, that harbors a hypomorphic mutation in the zinc finger protein Zfp335. Zfp335bloto/bloto mice exhibit a naïve...

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Bibliographic Details
Main Authors: Han, Brenda Y, Wu, Shuang, Foo, Chuan-Sheng, Horton, Robert M, Jenne, Craig N, Watson, Susan R, Whittle, Belinda, Goodnow, Chris C, Cyster, Jason G
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371841/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371841/

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