A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin

The pressor and antidiuretic actions of arginine vasopressin (AVP) have been well documented. This review focuses on the less widely appreciated actions of AVP which also have important physiologic functions and when better understood may provide important insights into common disease states. These...

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Main Authors:	Mavani, Gaurang P., DeVita, Maria V., Michelis, Michael F.
Format:	Online
Language:	English
Published:	Frontiers Media S.A. 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371647/

id	pubmed-4371647
recordtype	oai_dc
spelling	pubmed-43716472015-04-07 A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin Mavani, Gaurang P. DeVita, Maria V. Michelis, Michael F. Medicine The pressor and antidiuretic actions of arginine vasopressin (AVP) have been well documented. This review focuses on the less widely appreciated actions of AVP which also have important physiologic functions and when better understood may provide important insights into common disease states. These actions include effects on pain perception and bone structure as well as important relationships to the varied components of metabolic syndrome. These include effects on blood glucose, lipid levels, and blood pressure. AVP may also play a role in the progression of chronic kidney disease and effect physiologic changes relating to aging, abnormal social behavior, and cognitive function. Important cellular responses including cell proliferation, inflammation, and control of infection and their relationship to AVP are described. Finally, the effects of AVP on hemostasis and the hypothalamic–pituitary–adrenal axis are noted. The goal of this summary of the various actions of AVP is to direct attention to the potential benefits of research in these underemphasized areas of importance. Frontiers Media S.A. 2015-03-24 /pmc/articles/PMC4371647/ /pubmed/25853137 http://dx.doi.org/10.3389/fmed.2015.00019 Text en Copyright © 2015 Mavani, DeVita and Michelis. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Mavani, Gaurang P. DeVita, Maria V. Michelis, Michael F.
spellingShingle	Mavani, Gaurang P. DeVita, Maria V. Michelis, Michael F. A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin
author_facet	Mavani, Gaurang P. DeVita, Maria V. Michelis, Michael F.
author_sort	Mavani, Gaurang P.
title	A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin
title_short	A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin
title_full	A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin
title_fullStr	A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin
title_full_unstemmed	A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin
title_sort	review of the nonpressor and nonantidiuretic actions of the hormone vasopressin
description	The pressor and antidiuretic actions of arginine vasopressin (AVP) have been well documented. This review focuses on the less widely appreciated actions of AVP which also have important physiologic functions and when better understood may provide important insights into common disease states. These actions include effects on pain perception and bone structure as well as important relationships to the varied components of metabolic syndrome. These include effects on blood glucose, lipid levels, and blood pressure. AVP may also play a role in the progression of chronic kidney disease and effect physiologic changes relating to aging, abnormal social behavior, and cognitive function. Important cellular responses including cell proliferation, inflammation, and control of infection and their relationship to AVP are described. Finally, the effects of AVP on hemostasis and the hypothalamic–pituitary–adrenal axis are noted. The goal of this summary of the various actions of AVP is to direct attention to the potential benefits of research in these underemphasized areas of importance.
publisher	Frontiers Media S.A.
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371647/
_version_	1613202751394676736

A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin

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