An age-dependent alteration of the respiratory exchange ratio in the db/db mouse

The leptin receptor-deficient db/db mouse is a rodent model of type 2 diabetes and obesity. Diabetes in db/db mice shows an age-dependent progression, with early insulin resistance followed by an insulin secretory defect resulting in profound hyperglycemia. However, there is insufficient data on age...

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Bibliographic Details
Main Authors: Choi, Hye-Min, Kim, Hae Rim, Kim, Eun-Kyoung, Byun, Yong Sub, Won, Young-Suk, Yoon, Won-Ki, Kim, Hyoung-Chin, Kang, Jong-Goo, Nam, Ki-Hoan
Format: Online
Language:English
Published: Korean Association for Laboratory Animal Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371472/