Conjoined Use of EM and NMR in RNA Structure Refinement

More than 40% of the RNA structures have been determined using nuclear magnetic resonance (NMR) technique. NMR mainly provides local structural information of protons and works most effectively on relatively small biomacromolecules. Hence structural characterization of large RNAs can be difficult fo...

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Bibliographic Details
Main Authors: Gong, Zhou, Schwieters, Charles D., Tang, Chun
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370883/