Protein-Binding RNA Aptamers Affect Molecular Interactions Distantly from Their Binding Sites

Nucleic acid aptamer selection is a powerful strategy for the development of regulatory agents for molecular intervention. Accordingly, aptamers have proven their diligence in the intervention with serine protease activities, which play important roles in physiology and pathophysiology. Nonetheless,...

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Bibliographic Details
Main Authors: Dupont, Daniel M., Thuesen, Cathrine K., Bøtkjær, Kenneth A., Behrens, Manja A., Dam, Karen, Sørensen, Hans P., Pedersen, Jan S., Ploug, Michael, Jensen, Jan K., Andreasen, Peter A.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368798/