Alpha-Catulin Contributes to Drug-Resistance of Melanoma by Activating NF-κB and AP-1

Melanoma is the most dangerous type of skin cancer accounting for 48,000 deaths worldwide each year and an average survival rate of about 6-10 months with conventional treatment. Tumor metastasis and chemoresistance of melanoma cells are reported as the main reasons for the insufficiency of currentl...

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Bibliographic Details
Main Authors: Kreiseder, Birgit, Holper-Schichl, Yvonne M, Muellauer, Barbara, Jacobi, Nico, Pretsch, Alexander, Schmid, Johannes A., de Martin, Rainer, Hundsberger, Harald, Eger, Andreas, Wiesner, Christoph
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368766/