Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Tubular Epithelial Cell Dedifferentiation and Growth via Hepatocyte Growth Factor Induction

Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Tubular Epithelial Cell Dedifferentiation and Growth via Hepatocyte Growth Factor Induction

During acute kidney injury (AKI), tubular cell dedifferentiation initiates cell regeneration; hepatocyte growth factor (HGF) is involved in modulating cell dedifferentiation. Mesenchymal stem cell (MSC)-derived microvesicles (MVs) deliver RNA into injured tubular cells and alter their gene expressio...

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Bibliographic Details
Main Authors: Ju, Guan-qun, Cheng, Jun, Zhong, Liang, Wu, Shuai, Zou, Xiang-yu, Zhang, Guang-yuan, Gu, Di, Miao, Shuai, Zhu, Ying-jian, Sun, Jie, Du, Tao
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368636/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368636/

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