Multifunctional cytomegalovirus (CMV)-specific CD8+ T cells are not restricted by telomere-related senescence in young or old adults

Multifunctional cytomegalovirus (CMV)-specific CD8+ T cells are not restricted by telomere-related senescence in young or old adults

Antigen-specific multifunctional T cells that secrete interferon-γ, interleukin-2 and tumour necrosis factor-α simultaneously after activation are important for the control of many infections. It is unclear if these CD8+ T cells are at an early or late stage of differentiation and whether telomere e...

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Bibliographic Details
Main Authors: Riddell, Natalie E, Griffiths, Stephen J, Rivino, Laura, King, David C B, Teo, Guo H, Henson, Sian M, Cantisan, Sara, Solana, Rafael, Kemeny, David M, MacAry, Paul A, Larbi, Anis, Akbar, Arne N
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368162/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368162/

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