Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery

The purpose of this study was to develop a novel lipid–polymer hybrid drug carrier comprised of folate (FA) modified lipid-shell and polymer-core nanoparticles (FLPNPs) for sustained, controlled, and targeted delivery of paclitaxel (PTX). The core-shell NPs consist of 1) a poly(ε-caprolactone) hydro...

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Bibliographic Details
Main Authors: Zhang, Linhua, Zhu, Dunwan, Dong, Xia, Sun, Hongfan, Song, Cunxian, Wang, Chun, Kong, Deling
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368035/