Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure

Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure

Mitochondrial dysfunction and alterations in energy metabolism have been implicated in a variety of human diseases. Mitochondrial fusion is essential for maintenance of mitochondrial function and requires the prohibitin ring complex subunit prohibitin-2 (PHB2) at the mitochondrial inner membrane. He...

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Bibliographic Details
Main Authors: Ising, Christina, Koehler, Sybille, Brähler, Sebastian, Merkwirth, Carsten, Höhne, Martin, Baris, Olivier R, Hagmann, Henning, Kann, Martin, Fabretti, Francesca, Dafinger, Claudia, Bloch, Wilhelm, Schermer, Bernhard, Linkermann, Andreas, Brüning, Jens C, Kurschat, Christine E, Müller, Roman-Ulrich, Wiesner, Rudolf J, Langer, Thomas, Benzing, Thomas, Brinkkoetter, Paul Thomas
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364945/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364945/

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