Breeding scheme and maternal small RNAs affect the efficiency of transgenerational inheritance of a paramutation in mice
Paramutations result from interactions between two alleles at a single locus, whereby one induces a heritable change in the other. Although common in plants, paramutations are rarely studied in animals. Here, we report a new paramutation mouse model, in which the paramutant allele was induced by an...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363887/ |